SODIUM HYALURONATE

For human health and safety of life

Kikkoman is a Japanese company who appeared on the market for the first time in 1917 with soy sauce business, becoming the number one soy sauce producer in the world.
They have strengthened their presence on the market by specializing in the business of biochemicals, particularly in the ingredient for pharmaceutical sector with specific sodium hyaluronate pharmaceutical grade.

Obtained by microbial fermentation (by Streptococcus zooepidemicus), it can be used as API or functional ingredient for several applications.

Main applications:

Knee injection
Dermal filler
Ophthalamic

The line

It is composed by four different types of purified sodium hyaluronate which differ in the grade of intrinsic viscosity with low levels of endotoxin according to Ph. Eur. (0.05 EU):

GS-40
Intrinsic viscosity (m3/kg): 0.39 – 0.99
Molecular Weight (Dalton): 150.000 – 490.000
GS-100
Intrinsic viscosity (m3/kg): 1.00 – 2.49
Molecular Weight (Dalton): 500.000 – 1.600.000
GS-200
Intrinsic viscosity (m3/kg): 2.50 – 3.31
Molecular Weight (Dalton): 1.600.000 – 2.310.000
GS-300
Intrinsic viscosity (m3/kg): 3.32 – 4.60
Molecular Weight: 2.125.000 – 3.200.000
PG-80
Intrinsic viscosity (m3/kg): 1.2 – 2.0
Molecular Weight (Dalton): 630.000 – 1.210.000
Endotoxin (EU/mg): 0.0025