Ketoconazole impurity B

Ketoconazole is an antifungal medication used to treat a number of fungal infections. It interferes with the fungal synthesis of ergosterol, a constituent of fungal cell membranes, as well as certain enzymes.

By |2021-12-20T17:08:02+01:00December 20th, 2021|Comments Off on Ketoconazole impurity B

Hydroxy itraconazole

It’s a metabolite of Itraconazole, an orally active antimycotic structurally related to Ketoconazole. It inhibits the fungal-mediated synthesis of ergosterol, via inhibition of lanosterol 14α-demethylase.

By |2021-10-29T10:47:34+01:00October 29th, 2021|Comments Off on Hydroxy itraconazole

Ciclopirox D5

Ciclopirox is a synthetic antifungal agent for topical treatment of onychomycosis. Ciclopirox chelates polyvalent cations, resulting in inhibition of metal-dependent enzymes that are responsible for degrading peroxides inside fungal cells.

By |2021-10-29T09:33:52+01:00October 19th, 2021|Comments Off on Ciclopirox D5